What is the Role of Deletions in Cancer Prognosis?
The presence and specific patterns of deletions can significantly affect the prognosis of cancer patients. Certain deletions are associated with a poorer prognosis and resistance to treatment. For instance, deletions affecting the BRCA1/BRCA2 genes are linked to breast and ovarian cancers and can influence treatment decisions and survival outcomes. Identifying these deletions can help clinicians tailor treatment strategies and predict patient responses to therapies.
