What is the Role of DNA Adducts in Cancer Therapy?
Interestingly, DNA adducts also play a role in cancer therapy. Certain chemotherapeutic agents, like cisplatin, exert their anticancer effects by forming DNA adducts. These adducts disrupt cancer cell replication, leading to cell death. Understanding the balance between DNA damage and repair in cancer cells is crucial for optimizing therapeutic strategies and overcoming drug resistance.