What is the Role of T Cells in Cancer Immunotherapy?
T cells are pivotal in cancer immunotherapy due to their ability to specifically target and kill cancer cells. In therapies like CAR T-cell therapy, T cells are extracted from a patient, genetically engineered to express a receptor specific to cancer antigens, and then reintroduced into the patient's body. These modified T cells can then effectively recognize and destroy cancer cells. Additionally, adoptive cell transfer (ACT) involves the infusion of T cells that are naturally found in the tumor, expanded and activated ex vivo, and then reinfused into the patient.