What is the Significance of Non-Coding RNAs in Cancer?
Non-coding RNAs, particularly microRNAs (miRNAs), are key regulators of gene expression. They can function as oncogenes or tumor suppressors. Dysregulation of miRNAs has been linked to various cancers. For example, the miR-17-92 cluster is often amplified in lymphoma, acting as an oncogene by promoting cell proliferation and inhibiting apoptosis.
