Several epigenetic therapies are in development or already in use. These include:
- DNA Methyltransferase Inhibitors: Agents like azacitidine and decitabine are used to demethylate DNA, potentially reactivating tumor suppressor genes.
- Histone Deacetylase Inhibitors: Drugs such as vorinostat and romidepsin are used to modify histone acetylation, affecting gene expression patterns in cancer cells.
These therapies offer a promising avenue for treating cancers that are driven by epigenetic dysregulation.
