Natural Killer (NK) cells: These are the most significant effectors in ADCC due to their ability to recognize and kill antibody-coated cells without prior sensitization. Macrophages: These can also mediate ADCC by phagocytosing antibody-coated cells. Neutrophils and eosinophils: These granulocytes can contribute to ADCC by releasing cytotoxic substances that kill antibody-coated cells.
