What Types of Antibodies are Used in ADCC-Based Cancer Therapy?
Various monoclonal antibodies are designed to harness ADCC for cancer therapy. Some notable examples include:
Rituximab: Used in the treatment of B-cell non-Hodgkin lymphoma by targeting the CD20 antigen on B-cells. Trastuzumab: Used in HER2-positive breast cancer by targeting the HER2/neu receptor. Cetuximab: Used in metastatic colorectal cancer by targeting the epidermal growth factor receptor (EGFR).
