What is the significance of the tumor microenvironment?
The tumor microenvironment consists of the surrounding cells, blood vessels, and extracellular matrix that interact with cancer cells. It plays a crucial role in cancer progression and metastasis. Components such as fibroblasts, immune cells, and endothelial cells can either hinder or promote tumor growth. The interplay between cancer cells and the microenvironment is a target for therapeutic interventions.