Various methods are employed in mechanistic studies, including:
- Genomic Sequencing: Identifying mutations and alterations in the DNA of cancer cells. - Proteomics: Studying the protein expression and modifications in cancer cells. - Cell Culture Models: Using cancer cell lines to investigate cellular behaviors and drug responses. - Animal Models: Utilizing genetically engineered mice to study cancer development and test potential treatments. - Bioinformatics: Analyzing large datasets to identify patterns and correlations in cancer biology.