What Role do Cyclins and Cyclin-Dependent Kinases (CDKs) Play?
Cyclins and CDKs are essential for cell cycle progression. Cyclins are proteins that regulate the cell cycle by activating CDKs. CDKs, when bound to cyclins, phosphorylate target proteins to drive the cell cycle forward. Dysregulation of cyclins or CDKs can lead to unchecked cell division, a hallmark of cancer.
