What role do genetics play in alcohol-related cancer risk?
Genetics can influence an individual's susceptibility to alcohol-related cancers. Certain genetic variants can affect how the body metabolizes alcohol, particularly the conversion of ethanol to acetaldehyde. For instance, individuals with deficiencies in the enzyme aldehyde dehydrogenase 2 (ALDH2) may accumulate higher levels of acetaldehyde, increasing their cancer risk. Understanding one's genetic predisposition can help in making informed decisions about alcohol consumption.
