In cancer cells, metabolic pathways are often reprogrammed to support rapid proliferation and survival under stressful conditions. NADP+ is a key player in these metabolic changes. It acts as a hydrogen and electron acceptor, forming NADPH, which is crucial for biosynthetic reactions and maintaining the redox balance within the cell. NADPH is particularly important for the synthesis of fatty acids and nucleotides, as well as for neutralizing reactive oxygen species (ROS), which are often elevated in cancer cells.
