Are There Any Clinical Trials Targeting NADP+ Pathways in Cancer?
Currently, there are several ongoing clinical trials investigating the potential of targeting NADP+ metabolism in cancer. These trials are exploring inhibitors of enzymes like G6PD and isocitrate dehydrogenase (IDH), which are involved in NADPH production and regulation. The results of these trials could provide valuable insights into the feasibility and effectiveness of such therapeutic approaches.