Resistant Gram positive bacteria employ various mechanisms to evade antibiotics:
Enzymatic Degradation: Bacteria produce enzymes that deactivate antibiotics, such as beta-lactamases that degrade beta-lactam antibiotics. Altered Target Sites: Alterations in bacterial proteins that antibiotics target can render the drugs ineffective. Efflux Pumps: Some bacteria have pumps that expel antibiotics from their cells, reducing drug concentration to ineffective levels.
