What Role Does Proteomics Play in Understanding Cancer Metastasis?
Cancer metastasis, the spread of cancer cells from the primary site to other parts of the body, is a major cause of cancer-related mortality. Proteomics helps in understanding the molecular mechanisms underlying metastasis by identifying proteins involved in cell migration, invasion, and adhesion. For instance, proteins such as matrix metalloproteinases (MMPs) are known to facilitate the breakdown of extracellular matrix, aiding in cancer cell invasion and metastasis.