How Does Proteomics Contribute to Biomarker Discovery?
Biomarker discovery is one of the most significant contributions of proteomics to cancer research. By comparing the protein profiles of cancerous tissues with those of normal tissues, researchers can identify proteins that are differentially expressed. These differentially expressed proteins can serve as biomarkers for early diagnosis, prognosis, or treatment response. For example, the protein HER2 is a well-known biomarker for certain types of breast cancer, and its overexpression can guide targeted therapy.
