What Role Does Test Sensitivity and Specificity Play?
PPV is closely related to the sensitivity and specificity of a test. Sensitivity refers to the test's ability to correctly identify those with the disease (true positives), while specificity refers to correctly identifying those without the disease (true negatives). A test with high sensitivity and specificity will generally have a higher PPV. However, even a highly sensitive and specific test can have a low PPV in a population with low disease prevalence.
