What Role Does the Extracellular Matrix (ECM) Play in Cancer?
The ECM is a complex network of proteins and other molecules that provide structural support to tissues. In cancer, the ECM is often remodeled in ways that promote tumor progression. For example, increased ECM stiffness has been linked to enhanced cancer cell proliferation and invasion. Changes in ECM composition can also affect the delivery and efficacy of anti-cancer drugs. Understanding how cancer cells interact with the ECM is crucial for developing new therapeutic strategies.
