What Strategies Are Used to Improve Drug Solubility?
Pharmaceutical researchers employ several strategies to improve drug solubility, especially for cancer treatments:
Nanotechnology: Using nanoparticles to encapsulate the drug, enhancing solubility and targeting. Prodrug: Converting the drug into a more soluble form, which metabolizes into the active drug in the body. Solubilizing Agents: Adding substances like surfactants or co-solvents to increase solubility. Salt Formation: Converting the drug into a salt, which often has better solubility.