What Techniques are Used for Target Identification?
Several techniques are employed to identify potential targets in cancer:
Genomic Analysis: By sequencing the DNA of cancer cells, researchers can identify mutations and alterations that drive cancer progression. Proteomics: This involves studying the protein expression and interactions in cancer cells to identify abnormalities. RNA Interference (RNAi): RNAi can be used to silence specific genes and observe the effects on cancer cell survival, thereby identifying potential targets. CRISPR-Cas9: This gene-editing technology allows precise modifications in the genome to study the role of specific genes in cancer.