What Types of Bioreactors are Used in Cancer Research?
Several types of bioreactors are employed in cancer research, each with unique advantages:
- Stirred-Tank Bioreactors: Commonly used for large-scale cell culture, these bioreactors ensure uniform cell distribution and efficient nutrient mixing. - Rotating Wall Vessel Bioreactors: These create a low-shear environment, promoting the formation of 3D tumor spheroids which closely mimic the in vivo conditions. - Microfluidic Bioreactors: These miniaturized systems allow for precise control over the microenvironment, enabling detailed studies on cell behavior, drug response, and cell-to-cell interactions. - Perfusion Bioreactors: These continuously supply fresh nutrients and remove waste products, maintaining a stable and optimal environment for long-term culture of cancer cells.
