1. Laryngeal Cancer: This is perhaps the most direct cause of dysphonia. Tumors on the vocal cords or surrounding areas can lead to significant voice changes. 2. Thyroid Cancer: As the thyroid gland is located near the vocal cords, tumors or surgical interventions can affect the recurrent laryngeal nerve, leading to voice changes. 3. Lung Cancer: Particularly, left-sided lung cancer can impinge on the recurrent laryngeal nerve as it loops around the aorta, causing a condition known as recurrent laryngeal nerve palsy, which results in dysphonia. 4. Esophageal Cancer: Tumors in the esophagus can also press against the vocal cords or nerves, leading to voice changes.