What Types of Monoclonal Antibodies Are Used in Cancer Treatment?
There are several types of monoclonal antibodies used in cancer treatment, including:
Naked monoclonal antibodies: These work solely by attaching to cancer cells and do not carry any drugs or radioactive material. An example is Rituximab, used in certain types of lymphoma. Conjugated monoclonal antibodies: These are joined to a chemotherapy drug or a radioactive particle. They deliver these toxic substances directly to the cancer cells, minimizing damage to normal cells. An example is Brentuximab vedotin, used in Hodgkin lymphoma. Bispecific monoclonal antibodies: These are engineered to attach to two different antigens at the same time, which can bring cancer cells and immune cells together to promote a stronger immune response. An example is Blinatumomab, used in certain leukemias.
