LPA1 has been linked to various cancers, including breast, ovarian, prostate, and pancreatic cancers. In breast cancer, high levels of LPA1 are associated with increased risk of metastasis and poor prognosis. Similarly, in ovarian cancer, LPA1 facilitates the dissemination of cancer cells within the peritoneal cavity. In prostate cancer, LPA1 expression correlates with aggressive tumor characteristics, while in pancreatic cancer, it supports the invasive behavior of tumor cells.
