Which DNA Repair Genes are Commonly Implicated in Cancer?
Several DNA repair genes are frequently associated with cancer. For example, mutations in the BRCA1 and BRCA2 genes significantly increase the risk of breast and ovarian cancers. Similarly, defects in the MLH1 and MSH2 genes, which are involved in mismatch repair, are linked to Lynch syndrome, an inherited condition that elevates the risk of colorectal cancer and other cancers.
