growth factors

Which Growth Factors Are Commonly Involved in Cancer?

Several growth factors and their receptors are commonly associated with cancers:
Epidermal Growth Factor (EGF): Often implicated in cancers of the breast, lung, and colon.
Vascular Endothelial Growth Factor (VEGF): Plays a significant role in angiogenesis, the formation of new blood vessels, which is crucial for tumor growth and metastasis.
Platelet-Derived Growth Factor (PDGF): Frequently involved in gliomas and other cancers.
Transforming Growth Factor-beta (TGF-beta): Has dual roles, acting as a tumor suppressor in normal cells but promoting tumor progression in advanced cancers.

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