Cancer cells often exploit growth factors to facilitate their own survival and proliferation. They can achieve this through several mechanisms:
Overexpression: Cancer cells may produce excessive amounts of growth factors, leading to autocrine signaling loops that promote continuous cell division. Receptor Overexpression: Cancer cells may also overexpress receptors for growth factors, making them more sensitive to these signals. Mutations: Mutations in growth factor receptors can lead to their constant activation, even in the absence of the growth factor.
