Which Pro Apoptotic Proteins Are Commonly Studied in Cancer Research?
Several pro apoptotic proteins are extensively studied in cancer research, including:
- Bax: Promotes the release of cytochrome c from mitochondria. - Bak: Works in concert with Bax to permeabilize the mitochondrial membrane. - Bim: Binds and neutralizes anti apoptotic proteins. - Bid: Links the extrinsic and intrinsic apoptotic pathways. - Puma: Induced by p53 and promotes apoptosis in response to DNA damage.
