1. Mimicking the Tumor Microenvironment: They better replicate the tumor microenvironment compared to 2D cultures, which helps in understanding the intricate interactions between cancer cells and their surroundings. 2. Drug Testing and Development: These models provide a more realistic platform for testing the efficacy and toxicity of new cancer drugs, potentially reducing the failure rate in clinical trials. 3. Understanding Metastasis: 3D models can be used to study the mechanisms of cancer metastasis and identify key factors involved in the spread of cancer cells to distant organs.
