- Understanding Tumor Biology: They help decipher the complex biology of tumor initiation, progression, and metastasis. - Drug Development and Testing: Animal models are used to screen potential anti-cancer drugs for efficacy and toxicity before progressing to clinical trials. - Studying Tumor Microenvironment: They enable researchers to investigate the interactions between cancer cells and their surrounding stromal and immune cells. - Genetic Studies: GEMs, in particular, allow for the study of the role of specific genes in cancer development and progression.
