Why are Chromosomal Segregation Errors Significant in Cancer?
Chromosomal segregation errors are significant in cancer because they lead to genetic instability, a key characteristic of cancer cells. This instability allows for rapid evolution and adaptation, enabling cancer cells to develop resistance to treatments, invade tissues, and metastasize to distant organs. The presence of aneuploidy can also disrupt the function of tumor suppressor genes and oncogenes, further driving tumorigenesis.
