What is the Role of Segregation Errors in Cancer Therapy?
Understanding segregation errors can aid in the development of targeted cancer therapies. Drugs that exacerbate chromosomal instability may selectively kill cancer cells, which are more dependent on certain pathways for survival compared to normal cells. Conversely, stabilizing chromosome segregation in cancer cells could reduce their adaptability and resistance to treatment. Therefore, targeting segregation errors presents both opportunities and challenges in cancer therapy.
