Why are PBMC Humanized Mice Important in Cancer Research?
PBMC humanized mice are crucial in cancer research for several reasons. First, they provide a platform to study the interaction between the human immune system and cancer cells in a controlled environment. This is particularly important for understanding the mechanisms of [tumor immunology](). Second, they enable the evaluation of novel immunotherapies, including [checkpoint inhibitors]() and [CAR-T cell therapies](), in a human-specific context. Lastly, these models can be used to investigate the effects of new drugs on both the tumor and the immune system, offering insights into potential [combinatorial therapies]().
