Why are Regulatory Pathways Important for Cancer Therapy?
Understanding these pathways allows for the development of targeted therapies. For instance, mTOR inhibitors are used to treat cancers with hyperactive PI3K/AKT/mTOR signaling. Similarly, MEK inhibitors target the MAPK pathway in cancers with RAS or RAF mutations. Therapies targeting these pathways can be more effective and have fewer side effects compared to traditional chemotherapy.