Drug resistance is a significant obstacle in cancer treatment. Tumors can become resistant to chemotherapy, targeted therapies, and even immunotherapy. This occurs due to several mechanisms, including genetic mutations, epigenetic changes, and the tumor microenvironment. Overcoming drug resistance requires a better understanding of these mechanisms and the development of combination therapies that target multiple pathways. Additionally, continuous monitoring of tumor evolution through technologies like single-cell sequencing can help in adapting treatment plans in real-time.
