Why is GermlineCNVCaller Important in Cancer Research?
Understanding the genetic basis of cancer is crucial for early diagnosis, treatment, and prevention. Germline CNVs can contribute to cancer risk by disrupting key tumor suppressor genes or oncogenes. For example, deletions in genes like BRCA1 or BRCA2 are well-known to increase the risk of breast and ovarian cancers. By identifying these germline CNVs, researchers and clinicians can better understand an individual's genetic predisposition to cancer, enabling more personalized approaches to treatment and prevention.
