Why Is Glutamine Important in Cancer Biosynthesis?
Glutamine is a key amino acid that serves as a carbon and nitrogen source for cancer cells. It is involved in the synthesis of nucleotides, amino acids, and other macromolecules. Cancer cells often exhibit glutamine addiction, relying on it to maintain their metabolic flexibility and support rapid growth.
Targeting glutamine metabolism has become an area of interest in cancer therapy, as disrupting this pathway can potentially hinder cancer cell proliferation.