Why is Targeting VEGF Important in Cancer Therapy?
Targeting VEGF is crucial because inhibiting this pathway can starve the tumor of its blood supply, potentially shrinking the tumor and slowing disease progression. Anti-VEGF therapies, such as monoclonal antibodies (e.g., Bevacizumab) and small molecule inhibitors, have been developed to block VEGF signaling. These therapies aim to disrupt the vascular network of the tumor, making it more difficult for the tumor to grow and metastasize.
