What are the Challenges and Side Effects of Anti-VEGF Therapies?
While anti-VEGF therapies have shown promise, they are not without challenges. Resistance to these therapies can develop, as tumors may activate alternative pathways to sustain angiogenesis. Moreover, blocking VEGF can lead to side effects such as hypertension, impaired wound healing, and increased risk of thromboembolic events. Therefore, the efficacy and safety of anti-VEGF treatments must be carefully balanced.