Why is the AKT Pathway a Target for Cancer Therapy?
Given its prominent role in promoting cancer cell survival and proliferation, the AKT pathway is an attractive target for cancer therapy. Inhibitors of various components of the pathway, including PI3K inhibitors, AKT inhibitors, and mTOR inhibitors, are being developed and tested in clinical trials. These inhibitors aim to reduce tumor growth and sensitize cancer cells to other treatments like chemotherapy and radiotherapy.
