Why Is Understanding Sample Variability Important for Treatment?
Treatment decisions in cancer are often based on biomarkers identified in the tumor sample. Variability can lead to inconsistent biomarker expression, affecting the choice and efficacy of targeted therapies. For example, a patient might be prescribed a targeted therapy based on a specific mutation detected in the biopsy, but if the mutation is not present throughout the tumor, the treatment may not be effective. Understanding and accounting for sample variability can help in developing more effective treatment plans.