Single arm studies are particularly useful in oncology for several reasons:
Speed and Efficiency: They can be conducted more quickly than randomized controlled trials (RCTs), which is crucial when dealing with aggressive cancers. Ethical Considerations: In certain cases, it may be unethical to withhold potentially life-saving treatments from a control group, making single arm studies a more ethical choice. Early Signal Detection: These studies can provide early indications of a treatment's efficacy and safety, which can be invaluable for further research and development.