esophagus - Cancer Science

What is Esophageal Cancer?

Esophageal cancer is a type of cancer that occurs in the esophagus, the long, hollow tube that runs from your throat to your stomach. The esophagus helps move food and liquids from your mouth to your stomach for digestion.

Types of Esophageal Cancer

There are two main types of esophageal cancer:

Adenocarcinoma: This type typically starts in the mucus-secreting glands in the esophagus and is more common in the lower part of the esophagus. It is often associated with gastroesophageal reflux disease (GERD) and Barrett's esophagus.
Squamous Cell Carcinoma: This type occurs in the flat cells lining the esophagus and is more common in the upper and middle parts of the esophagus. Risk factors include smoking and excessive alcohol consumption.

What Are the Symptoms?

Symptoms of esophageal cancer can be subtle at first and may include:

Difficulty swallowing (dysphagia)
Unintentional weight loss
Chest pain, pressure or burning
Indigestion or heartburn
Coughing or hoarseness

How is Esophageal Cancer Diagnosed?

Diagnosis usually involves a combination of tests and procedures, including:

Endoscopy: A procedure where a flexible tube with a camera is used to view the esophagus.
Biopsy: A sample of tissue is taken from the esophagus for laboratory testing.
Imaging tests: These may include CT scans, PET scans, and X-rays to determine the extent of the cancer.

Treatment Options

Treatment for esophageal cancer depends on the stage of the cancer, the overall health of the patient, and personal preferences. Options include:

Surgery: This may involve removing part of the esophagus (esophagectomy) and sometimes nearby lymph nodes.

Relevant Publications

Discovery and validation of combined biomarkers for the diagnosis of esophageal intraepithelial neoplasia and esophageal squamous cell carcinoma.

Issue Release: 2024

Immunohistochemical characterization of interstitial cells and their relationship to motor neurons within the mouse esophagus.

Issue Release: 2024

Organ and function preservation in gastrointestinal cancer: Current and future perspectives on endoscopic ablation.

Issue Release: 2024

Single-Center Randomized Trial Comparing Feeding Jejunostomy with Nasojejunal Tube Placement in Patients Undergoing Transhiatal Esophagectomy Post-Neoadjuvant Therapy for Esophageal Cancer.

Issue Release: 2024

A Modified Fiberoptic Endoscopic Evaluation of Swallowing Evaluating Esophageal Dysphagia by a Capsule: A Pilot Study.

Issue Release: 2024

DESCRIPTION OF ESOPHAGOSTOMY TUBE PLACEMENT IN TWO GIANT ANTEATER () CADAVERS.

Issue Release: 2024

Single Cell RNA Sequencing of Human Eosinophils in Allergic Inflammation in the Esophagus.

Issue Release: 2024

Author Correction: Ghrelin and Leptin Have a Complex Relationship with Risk of Barrett\'s Esophagus.

Issue Release: 2024

A novel dose rate optimization method to maximize ultra-high dose rate coverage of critical organs-at-risk without compromising dosimetry metrics in proton pencil beam scanning FLASH radiotherapy.

Issue Release: 2024

Characteristics of chronic enteropathy associated with SLCO2A1 gene (CEAS) in children, a unique type of monogenic very early-onset inflammatory bowel disease.

Issue Release: 2024

Targeting TRIM40 signaling reduces esophagus cancer development: A mechanism involving in protection of oroxylin A.

Issue Release: 2024

Correlation between hemoglobin and the risk of common malignant tumors: a 1999-2020 retrospective analysis and causal association analysis.

Issue Release: 2024

KLF5 inhibition initiates epithelial-mesenchymal transition in non-transformed human squamous epithelial cells.

Issue Release: 2024

Gavage Strategy for Decoction Formula of Traditional Chinese Medicine in Osteosarcoma Model Mice.

Issue Release: 2024

Comparative evaluation of endoscopic anti-reflux mucosectomy and stretta radiofrequency ablation in the management of gastroesophageal reflux disease: insights from a retrospective multicenter cohort study.

Issue Release: 2024

Proximal esophageal adenocarcinoma: A rare case report.

Issue Release: 2024

Robotic-Assisted Ivor Lewis Esophagectomy.

Issue Release: 2024

Prominent black esophagus, Wischnewsky spots, and black duodenum in a fatal hypothermia case with an underlying diabetic ketoacidosis.

Issue Release: 2024

Alcohol-related diseases: from metabolism to the main effect on the body.

Issue Release: 2024

The relationship between perioperative central venous oxygen saturation and postoperative complications in highly invasive gastroenterological surgery.

Issue Release: 2024

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