Are There Any Biomarkers for ROS Activity in Cancer?
Several biomarkers can indicate ROS activity and oxidative stress in cancer, including:
- 8-oxo-2'-deoxyguanosine (8-oxo-dG): A marker of oxidative DNA damage. - Malondialdehyde (MDA): A marker of lipid peroxidation. - Protein carbonyls: Indicators of protein oxidation.
Monitoring these biomarkers can help in assessing the level of oxidative stress and the effectiveness of ROS-targeted therapies.
