What Are Some Challenges in Targeting ROS in Cancer Therapy?
One of the main challenges is the dual role of ROS in cancer. While low to moderate ROS levels promote cancer cell survival, high levels can induce cell death. Therefore, precise modulation of ROS levels is required to achieve therapeutic benefits without harming normal cells. Additionally, the efficacy of antioxidant supplements in cancer prevention and treatment is still under debate, as some studies have shown that they may actually protect cancer cells from ROS-induced damage.
