Are there any Therapeutic Strategies Targeting ANRIL?
Yes, several therapeutic strategies are being explored to target ANRIL:
RNA Interference (RNAi): Techniques such as siRNAs and short hairpin RNAs (shRNAs) can be used to silence ANRIL expression. Antisense Oligonucleotides: These are designed to bind to ANRIL RNA, blocking its function and promoting its degradation. CRISPR/Cas9: This gene-editing technology can be employed to delete or modify the ANRIL gene, disrupting its oncogenic functions.
