What are the mechanisms by which ANRIL influences Cancer?
ANRIL influences cancer through several mechanisms:
Epigenetic Regulation: ANRIL interacts with chromatin-modifying complexes such as PRC2 and Polycomb Repressive Complex 1 (PRC1) to silence tumor suppressor genes. Regulation of Apoptosis: ANRIL can modulate apoptosis-related pathways, affecting the balance between cell survival and programmed cell death. Cell Proliferation: By influencing key cell cycle regulators, ANRIL can enhance the proliferation of cancer cells.
