Are there potential therapeutic strategies for NBS-related cancers?
With advances in targeted therapies, there is potential for personalized treatment options for NBS-related cancers. Strategies that exploit the defective DNA repair pathways, such as PARP inhibitors, have shown promise in treating tumors with similar genetic backgrounds, like those seen in BRCA1 and BRCA2 mutations. Research into gene therapy and novel immunotherapies also holds potential for addressing the underlying genetic defects and enhancing immune response in NBS patients.
