nijmegen breakage syndrome

How is NBS managed in the context of cancer?

Management of NBS involves a multidisciplinary approach that addresses both the underlying disorder and the associated cancer risk. Regular screening for malignancies is crucial for early detection and treatment. Conventional cancer therapies, such as chemotherapy and radiation, pose significant challenges in NBS patients due to their heightened sensitivity to DNA damage. Therefore, treatment regimens must be carefully tailored to minimize harmful side effects while effectively targeting cancerous cells.

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