Are There Tools Available for Read Depth Normalization?
Yes, several tools are available for read depth normalization:
1. DESeq2: A statistical package for analyzing count data from RNA-Seq. 2. edgeR: Another package for differential expression analysis of RNA-Seq count data. 3. CNVkit: A toolkit for detecting CNVs from high-throughput sequencing data. 4. GATK: The Genome Analysis Toolkit provides various tools for data normalization and variant discovery.
